ASFV-EpiBase is a specialized database dedicated to antigens and epitopes of African swine fever virus (ASFV). ASFV is a highly contagious viral disease that threatens global pig production, causing severe economic losses and representing a major challenge for animal health and food security. Despite decades of research, no effective commercial vaccine is currently available, making the discovery of novel epitopes and vaccine candidates a critical priority.
ASFV-EpiBase has been developed to address this urgent need by providing a centralized, curated, and comprehensive resource for ASFV immunological data. It integrates information from experimentally validated studies as well as computational predictions, enabling researchers to:
- Explore antigens and epitopes specific to ASFV across multiple strains and isolates.
- Access detailed annotations on immune response, host species, antigen localization, and experimental evidence.
- Compare epitope profiles to support the design of multi-epitope vaccines, diagnostics, and immunotherapeutics.
- Bridge genomics and immunoinformatics, offering insights into ASFV antigenicity and immune evasion mechanisms
How to Cite
Paopit Siriarchawatana, Supawadee Ingsriswang and Anan Jongkaewwattana (2025). ASFV-EpiBase: A curated database of African swine fever virus antigens and epitopes.
Retrieved from https://epibase.tbrcnetwork.org/
Information Resources
Learn about the computational methods and prediction tools used in ASFV-EpiBase for identifying T-cell epitopes (cytotoxic and helper) and B-cell epitopes. Our database integrates multiple established algorithms including NetMHCpan, NetMHCIIpan, TCRLens, BepiPred 3.0, and other prediction methods.
More info →